Patent · US Active

Mechanical phenotyping of single cells: high throughput quantitative detection and sorting

US10302408B2 · kind B2 · utility

0Cited by

23References

15Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Amy Rowat · Cambridge, US
David J. Hoelzle · Columbus, US
Clara Chan · Los Angeles, US

Key dates

Filing date	Nov 5, 2013
Grant date	May 28, 2019
Priority date	—
Expiry date	Nov 5, 2033

Classification

Technology area (CPC G)Physics
CPC primaryG01N2291/02827
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

This invention provides methods and devices for the high-throughput characterization of the mechanical properties of cells or particles. In certain embodiments the devices comprise a micro fluidic channel comprising: an oscillating element on a first side of said channel; and a detecting element on a second side of said channel opposite said oscillating element, wherein said detecting element is configured to detect a force transmitted through a cell or microparticle by said oscillating element. In certain embodiments the devices comprise a microfluidic channel comprising an integrated oscillator and sensor element on one first side of said channel, wherein said sensor is configured to detect a force transmitted through a cell or microparticle by said oscillator.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.