Magnetic nanocompositions for highly sensitive molecular and cellular enrichment, purification and detection
US10302651B2 · kind B2 · utility
0Cited by
4References
13Claims
0Family size
Inventors
Key dates
| Filing date | Jun 29, 2018 |
| Grant date | May 28, 2019 |
| Priority date | — |
| Expiry date | Jun 29, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2446/86
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a method of capturing, enriching, purifying, detecting or measuring a cell in a sample at a sub-nanogram level comprising providing a nanocomposition, contacting the sample with the nanocomposition to form a mixture solution and allowing the binding of the cell with the nanocomposition, applying a magnetic field to the mixture, and evaluating the presence of or absence of the cell. The nanocomposition is capable of capturing or enriching an analyte at a sub-nanogram level, and comprise a nanostructure operably linked to an analyte-capturing member.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.