Oil-in-water emulsions that contain nucleic acids
US10307374B2 · kind B2 · utility
22Cited by
32References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 24, 2017 |
| Grant date | Jun 4, 2019 |
| Priority date | — |
| Expiry date | Apr 24, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention generally relates to cationic oil-in-water emulsions that can be used to deliver nucleic acid molecules, such as an RNA molecule. The emulsion particles comprise an oil core and a cationic lipid. The emulsion particles have an average diameter of about 80 nm to about 180 nm, and the emulsion have an N/P ratio of at least 1.1:1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.