Inhibition of tumor growth with aggregates of small molecules
US10308682B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Mar 6, 2014 |
| Grant date | Jun 4, 2019 |
| Priority date | — |
| Expiry date | Mar 6, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are fibrillar molecular aggregates, which are morphologically and phenotypically similar to oligomers of aberrant proteins. The molecular aggregates, formed by self-assembly of small hydrophobic molecules, prevent the growth of microtubules. This unprecedented mechanism of “self-assembly to interfere with self-organization” allows inhibition of the growth of cancer cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.