Gamma-AApeptides with potent and broad-spectrum antimicrobial activity
US10308686B2 · kind B2 · utility
0Cited by
2References
20Claims
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Assignee
Inventors
Key dates
| Filing date | Nov 30, 2018 |
| Grant date | Jun 4, 2019 |
| Priority date | — |
| Expiry date | Nov 30, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to a novel class of antimicrobial agents called γ-AApeptides. The current invention provides various categories of γ-AApeptides, for example, linear γ-AApeptides, cyclic γ-AApeptides, and lipidated γ-AApeptides. γ-AApeptides of the current invention are designed to exert antimicrobial activity while being stable and non-toxic. γ-AApeptides also do not appear to lead to the development of microbial resistance in treated microorganisms. Thus, the disclosed γ-AApeptides can be used for the treatment of various medical conditions associated with pathogenic microorganisms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.