Method for expressing, secreting and transferring functional microRNAs/siRNAs and application thereof
US10308932B2 · kind B2 · utility
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Key dates
| Filing date | Jun 21, 2013 |
| Grant date | Jun 4, 2019 |
| Priority date | — |
| Expiry date | Jun 21, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/35
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a microparticle comprising a functional microRNA/siRNA and application thereof. Specifically, disclosed is a use of a functional microRNA and/or siRNA, which is used to prepare a composition applied to a mammal. After the composition is applied, the microparticle is formed in a first part in an animal, and transported to a second part, which thereby improves physiological status of the second part or heals a disease of the second part. The second part is different from the first part. The use is beneficial for optimizing a dosing manner of the functional microRNA and/or siRNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.