Activity of Fe—S cluster requiring proteins
US10308964B2 · kind B2 · utility
0Cited by
52References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 1, 2016 |
| Grant date | Jun 4, 2019 |
| Priority date | — |
| Expiry date | Feb 17, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is related to a recombinant host cell, in particular a yeast cell, comprising a dihydroxy-acid dehydratase polypeptide. The invention is also related to a recombinant host cell having increased specific activity of the dihydroxy-acid dehydratase polypeptide as a result of increased expression of the polypeptide, modulation of the Fe—S cluster biosynthesis of the cell, or a combination thereof. The present invention also includes methods of using the host cells, as well as, methods for identifying polypeptides that increase the flux in an Fe—S cluster biosynthesis pathway in a host cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.