Substituted imidazo[1,2-a]pyrazines as luciferase substrates
US10308975B2 · kind B2 · utility
2Cited by
17References
16Claims
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Key dates
| Filing date | Feb 2, 2018 |
| Grant date | Jun 4, 2019 |
| Priority date | — |
| Expiry date | Feb 2, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/90241
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described are substituted imidazo[1,2-a]pyrazine compounds, which are coelenterazine analogs, kits comprising the compounds, and methods of using the compounds for the detection of luminescence in luciferase-based assays. Also described are methods for making the compounds, such as a method using aminopyrazine acetophosphonates as synthesis intermediates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.