Methods for diagnosing risk of renal allograft fibrosis and rejection
US10308985B2 · kind B2 · utility
3Cited by
0References
19Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 26, 2015 |
| Grant date | Jun 4, 2019 |
| Priority date | — |
| Expiry date | Jun 26, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein is a method for diagnosing a renal allograft recipient's risk for developing fibrosis of the allograft and allograft loss. The method includes determining the expression levels of certain microRNAs, which have been determined to be predictive of an allograft recipient's risk. Also disclosed herein is a method of treating a renal allograft recipient to inhibit fibrosis of the allograft and allograft loss, as well as kits for use in the methods disclosed herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.