3.4 kb mitochondrial DNA deletion for use in the detection of cancer
US10308987B2 · kind B2 · utility
4Cited by
10References
17Claims
0Family size
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Key dates
| Filing date | Mar 27, 2017 |
| Grant date | Jun 4, 2019 |
| Priority date | — |
| Expiry date | Mar 27, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for detecting cancer in an individual comprising detecting a deletion in the nucleic acid sequence between residues 10743 and 14125 in mitochondrial DNA, obtaining a biological sample from the individual, extracting the mitochondrial DNA (mtDNA) from the sample, quantifying the amount of mtDNA in the sample having a deletion in the nucleic acid sequence between residues 10743 and 14125 of the mtDNA genome, and comparing the amount of mtDNA in the sample having the deletion to at least one known reference sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.