Methods of evaluating a cellular sample for latent cellular replication competent HIV-1
US10308990B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Jul 23, 2015 |
| Grant date | Jun 4, 2019 |
| Priority date | — |
| Expiry date | Jul 23, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M23/08
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods of evaluating a cellular sample for latent cellular replication competent HIV-1 are provided. Aspects of the methods include contacting a cellular sample with an HIV-1 inducing compound to produce an activated cellular sample; and assessing plasma viral load in the activated cellular sample to evaluate the cellular sample for latent cellular replication competent HIV-1. Also provided are devices and kits that find use in practicing the methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.