Method for amplifying signals from individual nerve fascicles

US10314725B2 · kind B2 · utility

Assignee

• THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US

Inventors

• Cynthia Anne Chestek · Ann Arbor, US
• Melanie G. Urbanchek · Ann Arbor, US
• Paul S. Cederna · Grass Lake, US
• Richard Brent GILLESPIE · Redwood City, US
• Nicholas B. Langhals · Ypsilanti, US
• Zachary Irwin · Ann Arbor, US
• Daniel C. Ursu · Ann Arbor, US

Key dates

• Filing date: Nov 13, 2015
• Grant date: Jun 11, 2019
• Expiry date: Feb 16, 2036

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61F2002/7635
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The present disclosure provides methods and systems for receiving, with processing circuitry of an implant device, an electrical signal from a free tissue graft attached to a portion of a nerve (e.g., a nerve branch or fascicle) through an electrical conductor in electrical communication with the free tissue graft (e.g., muscle graft), the nerve having reinnervated the free tissue graft. The electrical signal from the free tissue graft has a voltage amplitude of greater than or equal to about 150 microvolts. The processing circuitry stores signal data corresponding to the electrical signal from the free tissue graft in a memory accessible to the processing circuitry.