Process of synthesizing substituted pyridine and pyrimidine compound

US10316033B2 · kind B2 · utility

Assignees

• SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES · CN
• SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD. · CN

Inventors

• Jingkang Shen · Shanghai, CN
• Tao Meng · North Plainfield, US
• Ting YU · Shanghai, CN
• Lanping Ma · Shanghai, CN
• Xin Wang · Shanghai, CN
• Lin CHEN · Chengdu, CN

Key dates

• Filing date: Mar 24, 2016
• Grant date: Jun 11, 2019
• Expiry date: Mar 24, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Provided is a process of synthesizing a substituted pyridine and pyrimidine compound. Particularly, provided is a method for preparing a compound of formula III via a compound of formula II′, wherein the definition of each of groups is as described as the description. Compound with other methods, the method in the present invention has features of high yield and a result product being easier to separate.