Substituted pyrrolo[3,4-c]pyrazoles as pkc kinase inhibitors
US10316045B2 · kind B2 · utility
3Cited by
3References
16Claims
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Key dates
| Filing date | Dec 12, 2016 |
| Grant date | Jun 11, 2019 |
| Priority date | — |
| Expiry date | Dec 12, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds and pharmaceutically acceptable salts of Formulas A and B: wherein A, B, R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined above. The invention further relates to pharmaceutical compositions comprising the compounds and pharmaceutically acceptable salts and to methods of treating diabetes mellitus and its complications, cancer, ischemia, inflammation, central nervous system disorders, cardiovascular disease, Alzheimer's disease and dermatological disase pression, virus diseases, inflammatory disorders, or diseases in which the liver is a target organ.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.