Patent · US Active

Cyclic RGD cell-binding motif and uses thereof

US10316069B2 · kind B2 · utility

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20Claims

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Assignee

SPIBER TECHNOLOGIES AB · SE

Inventor

My Hedhammar · Stockholm, SE

Key dates

Filing date	Jun 23, 2016
Grant date	Jun 11, 2019
Priority date	—
Expiry date	Jun 23, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2533/50
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A recombinant fusion protein is comprising a spider silk fragment and a cyclic RGD cell-binding motif with selectivity for integrins, such as for α5β1 integrins. The fusion protein is useful as a cell scaffold material and for the cultivation of cells displaying integrins on their cell surface.

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