Patent · US Active

Cell-penetrating ATF5 polypeptides and uses thereof

US10316077B2 · kind B2 · utility

2Cited by

13References

20Claims

0Family size

Assignee

Sapience Therapeutics, Inc. · DE

Inventors

Barry Jay Kappel · Pelham, US
Jimmy Andrew Rotolo · New York, US
Gene Merutka · Hillsborough, US

Key dates

Filing date	Feb 17, 2018
Grant date	Jun 11, 2019
Priority date	—
Expiry date	Feb 17, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided are cell-penetrating ATF5 polypeptides having a cell-penetrating region and an ATF5 leucine zipper region, compositions comprising the ATF5 polypeptides, and methods of treating a tumor and promoting cytotoxicity in a neoplastic cell using the ATF5 polypeptides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.