Prion protein antibodies for the treatment of Alzheimer's disease
US10316099B2 · kind B2 · utility
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1References
24Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 8, 2016 |
| Grant date | Jun 11, 2019 |
| Priority date | — |
| Expiry date | Aug 13, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a ligand capable of binding PrP at a site within amino acid residues 131 to 153 of PrP, for use in treatment or prevention of impaired synaptic plasticity. The invention also relates to a ligand capable of binding PrP at a site within amino acid residues 131 to 153 of PrP, for use in treatment or prevention of toxicity of Aβ oligomers. The invention also relates to a ligand capable of binding PrP at a site within amino acid residues 131 to 153 of PrP, for use in treatment or prevention of Alzheimer's Disease. The invention also relates to methods of medical treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.