Patent · US Active

Use of aptamers in proteomics

US10316349B2 · kind B2 · utility

3Cited by

1References

26Claims

0Family size

Assignee

Caris Science, Inc. · US

Inventors

Clive Gavin Brown · Cambridge, GB
Koen Kas · Schilde, BE
Sven Eyckerman · Nazareth, BE

Key dates

Filing date	Aug 4, 2017
Grant date	Jun 11, 2019
Priority date	—
Expiry date	Aug 4, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/11
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention is a method for measuring the amount of at least one molecule in a biological sample, the method comprising a) combining the sample, or a derivative thereof, with one or more aptamers and allowing one or more molecules in the sample to bind to the aptamer(s); b) separating bound from unbound molecules; and c) quantifying the molecule(s) bound to the or each aptamer, wherein quantification of the bound molecule(s) is carried out by sequencing at least part of the or each aptamer. Uses of and products derived from the method are also contemplated.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.