18F-saccharide-folates
US10322195B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Aug 21, 2012 |
| Grant date | Jun 18, 2019 |
| Priority date | — |
| Expiry date | Sep 17, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein the 18F isotope F is linked via a prosthetic group, more specifically via a prosthetic group having a saccharide group, such as a cyclic mono- or oligosaccharide, preferably based on a pyranoside or furanoside, which is covalently linked to the glutamate portion of a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.