Patent · US Active

CRISPR-based methods and products for increasing frataxin levels and uses thereof

US10323073B2 · kind B2 · utility

4Cited by

0References

17Claims

0Family size

Assignee

Université Laval · CA

Inventors

Jacques P. Tremblay · Laurelbrook Court, CA
Pierre Chapdelaine · Lévis, CA
Joël Rousseau · Keyano, CA

Key dates

Filing date	Mar 20, 2015
Grant date	Jun 18, 2019
Priority date	—
Expiry date	Mar 20, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2310/20
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Methods and products (e.g., gRNAs, recombinant fusion proteins, frataxin targeting systems, compositions and kits) are described for increasing frataxin expression/levels in a cell, as well as uses of such methods and products, for example for the treatment of Friedreich ataxia in a subject suffering therefrom.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.