Polymer and crosslinked body thereof

US10323132B2 · kind B2 · utility

Assignees

• NOF CORPORATION · JP
• THE UNIVERSITY OF TOKYO · JP

Inventors

• Kazuhiko Ishihara · Tokyo, JP
• Yuuki Inoue · Tokyo, JP
• Kyoko Fukazawa · Tokyo, JP
• Masaru Matsuda · Yokohama, JP
• Satoshi Yamada · Yokohama, JP
• Tomozumi Noda · Kawasaki, JP

Key dates

• Filing date: Mar 2, 2016
• Grant date: Jun 18, 2019
• Expiry date: Aug 12, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08J2343/02
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Provided are a copolymer having enough biocompatibility to be used in a medical material application, and a method of forming a crosslinked body, which involves modifying a substrate surface with the copolymer so that the surface may be biocompatible. More specifically, a protein adsorption-suppressing effect and a cell adhesion-suppressing effect, which are features of a phosphorylcholine group, are imparted to the substrate surface. It has been found that the object is achieved by a copolymer containing a phosphorylcholine constitutional unit, a hydrophobic constitutional unit, and a photoreactive constitutional unit at a specific ratio.