Polyhydroxyalkanoate copolymer compositions and methods of making the same

US10323261B2 · kind B2 · utility

Assignee

• CJ CHEILJEDANG CORPORATION · KR

Inventors

• Thomas M. Ramseier · Newton, US
• Jeffrey A. Bickmeier · Arlington, US
• William R. Farmer · Concord, US
• Catherine Morse · Melrose, US
• Himani Chinnapen · Quincy, US
• Oliver P. Peoples · Arlington, US
• Yossef Shabtai · Ramat HaSharon, IL

Key dates

• Filing date: Oct 17, 2017
• Grant date: Jun 18, 2019
• Expiry date: Oct 17, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08L2201/06
• WIPO field: Macromolecular chemistry, polymers
• WIPO sector: Chemistry

Abstract

A polyhydroxyalkanoate copolymer composition is provided. The composition comprises a plurality of polyhydroxyalkanoate copolymer molecules. The polyhydroxyalkanoate copolymer molecules (i) comprise 3-hydroxybutyrate monomers and 4-hydroxybutyrate monomers, (ii) have a monomeric molar percentage of 4-hydroxybutyrate monomers of 23.5 to 75%, and (iii) have a biobased content of ≥80%. Also provided is a method of making a polyhydroxyalkanoate copolymer composition. The method comprises culturing an organism in the presence of one or more carbon raw materials under conditions under which (a) the one or more carbon raw materials are converted to 3-hydroxybutyryl-CoA and 4-hydroxybutyryl-CoA and (b) the 3-hydroxybutyryl-CoA and the 4-hydroxybutyryl-CoA are polymerized to form the polyhydroxyalkanoate copolymer molecules, thereby forming the composition. The organism has been genetically engineered to comprise particular enzymatic activities, and to not comprise other particular enzymatic activities. The one or more carbon raw materials, taken together, have a biobased content of ≥80%.