Probe reagent and fish using probe reagent
US10323271B2 · kind B2 · utility
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Key dates
| Filing date | Mar 20, 2015 |
| Grant date | Jun 18, 2019 |
| Priority date | — |
| Expiry date | Apr 9, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6841
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are: a probe reagent which is capable of stably yielding a fluorescence signal in FISH while inhibiting non-specific adsorption by the use of a nucleic acid molecule having a smaller number of bases than a BAC probe; and FISH using the probe reagent. The probe reagent is for in situ hybridization and comprises: phosphor-integrated nanoparticles containing phosphors integrated therein; and a nucleic acid molecule having a prescribed nucleic acid sequence, which phosphor-integrated nanoparticles and nucleic acid molecule are bound with each other.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.