Nucleic acid probes for in situ hybridization
US10323272B1 · kind B1 · utility
15Cited by
2References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 2, 2018 |
| Grant date | Jun 18, 2019 |
| Priority date | — |
| Expiry date | Aug 2, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6897
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides nucleic acid hybridization probes having improved detectability that include a plurality of first segments consecutively complementary to a target nucleic acid sequence and, between neighboring first segments, a nucleic acid spacer segment which is not complementary to the target nucleic acid sequence and which may include labeled nucleic acid residues. Also provided by the invention are methods for making the probes, methods for using the probes, and compositions of matter that include the probes hybridized to target nucleic acid molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.