Solubilizing agents for active or functional organic compounds

US10328003B2 · kind B2 · utility

Assignee

• ISP Investments LLC · US

Inventors

• Ilya Makarovsky · Fair Lawn, US
• Michael A. Tallon · Aberdeen, US
• Hani Fares · Somerville, US
• Donald I. Prettypaul · Englewood, US
• Krishnamurthy Nacharaju · Hilliard, US
• Anna A. Gripp · Nutley, US
• Osama M. Musa · Fryeburg, US

Key dates

• Filing date: Jun 10, 2016
• Grant date: Jun 25, 2019
• Expiry date: Jun 10, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A photo protective topical composition, comprising: (i) at least one functional active; and (ii) at least one solubilizing compound having the structure of Formula I: wherein R is C5-C10 cycloalkyl or linear or branched alkylcycloalkyl, wherein the ring size is C5-C7; R1, R2, and R3 are each independently selected from the group consisting of H, and linear or branched C1-C4 alkyl, provided that at least two of R1, R2, R3 are H; wherein the solubilizing compound is present in an amount effective to solubilize said functional active. Also disclosed is a method for treating skin, lips, nails, hair, ears, eyelashes, eyebrows and/or scalp with an effective amount of composition.