Nanofibrous materials as drug, protein, or genetic release vehicles
US10328032B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 2, 2014 |
| Grant date | Jun 25, 2019 |
| Priority date | — |
| Expiry date | Jun 2, 2034 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB29C48/022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is a bioactive, nanofibrous material construct which is manufactured using a unique electrospinning perfusion methodology. One embodiment provides a nanofibrous biocomposite material formed as a discrete textile fabric from a prepared liquid admixture of (i) a non-biodegradable durable synthetic polymer; (ii) a biologically active agent; and (iii) a liquid organic carrier. These biologically-active agents are chemical compounds which retain their recognized biological activity both before and after becoming non-permanently bound to the formed textile material; and will become subsequently released in-situ as discrete freely mobile agents from the fabric upon uptake of water from the ambient environment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.