TRPA1 and TRPV4 inhibitors and methods of using the same for organ-specific inflammation and itch
US10329265B2 · kind B2 · utility
3Cited by
5References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 22, 2014 |
| Grant date | Jun 25, 2019 |
| Priority date | — |
| Expiry date | Aug 22, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are methods of treating and/or preventing dermatological disorders. Provided are methods of reducing skin inflammation, reducing pain, and/or reducing itch in a subject in need thereof. The methods may include administering to the subject an effective amount of a TRPA1 and/or TRPV4 inhibitor. Further provided are compositions including a TRPA1 and/or TRPV4 inhibitor compound in combination with a carrier, vehicle, or diluent that is suitable for topical application.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.