Patent · US Active

Indole carboxamide compounds

US10329274B2 · kind B2 · utility

0Cited by
11References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 1, 2018
Grant dateJun 25, 2019
Priority date
Expiry dateFeb 1, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR4 or N; R1, R2, R3, R4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.