Patent · US Active

Neuroactive steroids, compositions, and uses thereof

US10329320B2 · kind B2 · utility

14Cited by
31References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 19, 2016
Grant dateJun 25, 2019
Priority date
Expiry dateFeb 19, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J21/008
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein R1, R2, Ra, G, X, Y, Z, and n are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. Also provided are pharmaceutical compositions comprising a compound described herein and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.