Engineered cascade components and cascade complexes
US10329547B1 · kind B1 · utility
9Cited by
5References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Jan 30, 2019 |
| Grant date | Jun 25, 2019 |
| Priority date | — |
| Expiry date | Jan 30, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/80
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides engineered Class 1 Type I CRISPR-Cas (Cascade) systems that comprise multi-protein effector complexes, nucleoprotein complexes comprising Type I CRISPR-Cas subunit proteins and nucleic acid guides, polynucleotides encoding Type I CRISPR-Cas subunit proteins, and guide polynucleotides. Also, disclosed are methods for making and using the engineered Class 1 Type I CRISPR-Cas systems of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.