Canine adenovirus vectors

US10329586B2 · kind B2 · utility

Assignee

• BOEHRINGER INGELHEIM VETMEDICA GMBH · DE

Inventors

• Andreas Gallei · Hannover, DE
• Ramesh Koukuntla · Ames, US
• Robert Mandell · Moraga, US
• Alice Mundt · Altwarmbüchen, DE
• Kristina Rehmet · Hannover, DE
• Eric Martin Vaughn · Ames, US

Key dates

• Filing date: Sep 18, 2017
• Grant date: Jun 25, 2019
• Expiry date: Sep 18, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2830/60
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to the field of CAdV vector vaccines, and especially to promoters suitable to express target antigens from such vector vaccines. Disclosed and claimed are recombinant canine adenoviruses, methods of making them, uses for them (including in immunological, immunogenic, vaccine or therapeutic compositions, or, as a vector for cloning, replicating or expressing DNA and methods of using the compositions and vector), expression products from them, and uses for the expression products. Additionally, disclosed and claimed are truncated EHV4 promoters, expression cassettes containing the promoters, and recombinant viruses and plasmids containing the promoters or expression cassettes.