Biochemical markers of platelet storage
US10330668B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 21, 2014 |
| Grant date | Jun 25, 2019 |
| Priority date | — |
| Expiry date | Nov 29, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/7066
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Compositions and methods determines post-transfusion survival of platelets and the suitability of platelet units for transfusion by measuring the levels of one or more markers in a platelet sample. A method determines post-transfusion survival of platelets (PL T) prior to transfusion, the method comprising the steps of: a) measuring the levels of one or more markers in a PL T sample selected from the group consisting of adenine, 13-HODE/9-HODE, Caprylate, Laurate, C-glycosyltryptophan, andro steroid monsulfate 2, and Unelucidated Compounds (UC) 1-4; b) comparing the level of the one or more markers in the PLT sample with the level of the one or more markers present in a control sample, wherein a higher or lower level of the one or more markers in the PL T sample is indicative of post-transfusion survival of platelets.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.