Mutant OPAA enzyme with increased catalytic efficiency on organophosphorus compound GP
US10335465B1 · kind B1 · utility
1Cited by
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8Claims
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Key dates
| Filing date | Jan 26, 2018 |
| Grant date | Jul 2, 2019 |
| Priority date | — |
| Expiry date | Jan 26, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA62D2101/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed toward mutant, non-wild-type organophosphorus acid anhydrolase enzymes having three site mutations, methods of production, and methods of use to effectively degrade toxic organophosphorus compounds, most preferably GP (2,2′-dimethylcyclopentyl methylphosphonofluoridate).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.