Patent · US Active

Phage-displayed antibody libraries and uses thereof

US10336815B2 · kind B2 · utility

0Cited by

1References

8Claims

0Family size

Assignee

ACADEMIA SINICA · TW

Inventors

An-Suei Yang · Emeryville, US
Ing-Chien Chen · Taipei, TW
Chao-Ping TUNG · Taipei, TW
Chung-Ming Yu · Taipei, TW

Key dates

Filing date	Aug 10, 2016
Grant date	Jul 2, 2019
Priority date	—
Expiry date	Oct 12, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed herein are phage-displayed single-chain variable fragment (scFv) libraries, which comprised a plurality of scFvs with a specific sequence in each CDR. The present scFv libraries could be used to efficiently produce different antibodies with high binding affinity to H1 hemagglutinin of influenza virus. Accordingly, the present disclosure provides a potential means to generate different antigen-specific antibodies promptly in accordance with the need in experimental researches and/or clinical applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.