Method and apparatus for analyzing biomolecules using Raman spectroscopy
US10338078B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 13, 2013 |
| Grant date | Jul 2, 2019 |
| Priority date | — |
| Expiry date | Aug 13, 2033 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/0418
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides an apparatus having a sample separation unit, a Raman spectroscopy unit, and a mass spectrometry unit. The present invention further provides a method for specifying a biomolecule and a method for identifying the binding site of the biomolecule and the low-molecular-weight compound, comprising a combination of Raman spectroscopy and mass spectrometry. The present invention further provides a surface-enhanced Raman spectroscopy method with improved sensitivity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.