Method for magnetic particle imaging having unlimited axial field of view

US10338161B2 · kind B2 · utility

Assignee

• UNIVERSITAET ZU LUEBECK · DE

Inventors

• Thorsten Buzug · Hamburg, DE
• Christian Kaethner · Forchheim, DE
• Mandy Gruettner · Stade, DE
• Gael Bringout · Stade, DE
• Matthias Weber · Uttenreuth, DE

Key dates

• Filing date: Nov 29, 2013
• Grant date: Jul 2, 2019
• Expiry date: Jan 23, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01R33/38
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention relates to a method and an MPIS scanner for tomographic imaging of an object with magnetic particles distributed in the interior of the object, comprising the steps of generating a selection magnetic field with a predetermined magnetic field gradient in at least one field-free point (FFP) in a predetermined scanning plane, generating a time-dependent, periodic excitation magnetic field with a predetermined maximum frequency, repeatedly displacing the at least one FFP along a predetermined closed trajectory with a predetermined repetition time in the scanning plane, moving the object through the scanning plane along a predetermined advance direction with a predetermined advance speed, detecting the change in the magnetization state of the magnetic particles at the points in the object interior through which the at least one FFP passes, reconstructing the local particle concentrations at the points through which the at least one FFP passes in respect of an object coordinate system, interpolating the reconstructed particle concentration to the points in the object interior not passed through by at least one FFP, generating a display of the particle concentration distribu…