Anti-parasitic complexes

US10344082B2 · kind B2 · utility

Assignee

• Fraunhofer-Gesellschaft zur förderung der angewandten Forschung e.V. · DE

Inventors

• Rolf Fendel · Aachen, DE
• Stephanie Kapelski · Ekeren, BE
• Stefan Barth · Jena, DE
• Rainer Fischer · Monschau, DE
• Andreas Reimann · Krefeld, DE

Key dates

• Filing date: Aug 21, 2015
• Grant date: Jul 9, 2019
• Expiry date: Aug 21, 2035

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The technology provided herein relates to novel anti-parasitic complexes, in particular recombinant fusion proteins suitable as human and/or animal drugs against a parasite of the phylum Apicomplexa, in particular against Plasmodium falciparum (P. falciparum) comprising at least one component A and at least one component B, characterized in that component A has a binding activity for cellular surface structures presented on the surface of a parasite of the phylum Apicomplexa or for parasitic antigens presented on a parasitized host cell, and component B is a compound having anti-parasitic activity.