DNA vectors, transposons and transposases for eukaryotic genome modification
US10344285B2 · kind B2 · utility
4Cited by
11References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 6, 2016 |
| Grant date | Jul 9, 2019 |
| Priority date | — |
| Expiry date | Oct 6, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/865
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides polynucleotide vectors for high expression of heterologous genes. Some vectors further comprise novel transposons and transposases that further improve expression. Further disclosed are vectors that can be used in a gene transfer system for stably introducing nucleic acids into the DNA of a cell. The gene transfer systems can be used in methods, for example, gene expression, bioprocessing, gene therapy, insertional mutagenesis, or gene discovery.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.