Patent · US Active

Method for identification and quantification of nucleic acid expression, splice variant, translocation, copy number, or methylation changes

US10344321B2 · kind B2 · utility

0Cited by

0References

30Claims

0Family size

Assignee

Cornell University · IT

Inventors

Francis Barany · Baltimore, US
John William Efcavitch · San Carlos, US
Cristian Ruiz Rueda · San Fernando, US
Jianmin Huang · New York, US
Philip B. Feinberg · New York, US

Key dates

Filing date	Oct 8, 2015
Grant date	Jul 9, 2019
Priority date	—
Expiry date	Jan 26, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/156
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to methods and devices for identifying and quantifying, including low abundance, nucleotide base mutations, insertions, deletions, translocations, splice variants, miRNA variants, alternative transcripts, alternative start sites, alternative coding sequences, alternative non-coding sequences, alternative splicings, exon insertions, exon deletions, intron insertions, or other rearrangement at the genome level and/or methylated nucleotide bases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.