Enamel products and methods of use

US10350147B2 · kind B2 · utility

Assignee

• The Research Foundation for The State University of New York · US

Inventors

• Stephanos Kyrkanides · Lexington, US
• Li Ma · Statesboro, US
• Sabine Brouxhon · Lexington, US

Key dates

• Filing date: Apr 27, 2015
• Grant date: Jul 16, 2019
• Expiry date: Apr 27, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G16H20/40
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described herein are three-dimensional (3D) culture systems that can be used to produce enamel organoids that generate enamel products. The invention features methods of culturing a variety of cell types to produce such enamel organoids; the organoids themselves; enamel products generated by the organoids; and methods of fashioning the enamel products into surgical restorations, including dental restorations and other prostheses.