Patent · US Active

MCJ agonists and uses therefor

US10350262B2 · kind B2 · utility

0Cited by
6References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 18, 2016
Grant dateJul 16, 2019
Priority date
Expiry dateFeb 18, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/10
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates, in part, to compounds, compositions, and methods useful to treat cancer in cells and subjects. In some aspects the invention includes contacting a cancer cell with one or more exogenous methylation-controlled J protein (MCJ) agonist compounds to increase sensitivity of the cancer cell to one or more chemotherapeutic agents. In certain aspects the invention includes compounds and methods useful to kill cancer cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.