Patent · US Active

Quinoline-3-carboxamide compounds and their use in diagnosis

US10350315B2 · kind B2 · utility

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9Claims

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Assignee

WESTFÄLISCHE WILHELMS-UNIVERSITÄT MÜNSTER · DE

Inventors

Andreas Faust · Billerbeck, DE
Sven Hermann · Munster, DE
Johannes Roth · Munster, DE
Michael Schaefers · Munster, DE
Thomas Vogl · Graz, AT

Key dates

Filing date	Oct 29, 2015
Grant date	Jul 16, 2019
Priority date	—
Expiry date	Oct 29, 2035

Classification

Technology area (CPC G)Physics
CPC primaryG06T2207/10132
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present application provides quinoline-3-carboxamide compounds covalently linked to a label for use in the diagnosis of an inflammatory disease at local site. The above mentioned compounds can be used to detect or image accumulation of S100A9 in the body of a subject at sites of inflammation, using in vivo non-invasive molecular imaging techniques for the detection of said compounds. Accordingly, labeled quinoline-3-carboxamide compounds can be applied to evaluate the risk of a subject of developing an inflammatory disease and to follow the progress of the disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.