Crystalline forms of lesinurad and its sodium salt
US10351536B2 · kind B2 · utility
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Key dates
| Filing date | Nov 20, 2014 |
| Grant date | Jul 16, 2019 |
| Priority date | — |
| Expiry date | Dec 1, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel crystalline forms of lesinurad and its sodium salt, processes for their preparation, pharmaceutical compositions comprising these new forms, and use of them for treating or delaying progression or onset of diseases or disorders related to activity of uric acid transporter 1 (URAT1) proteins are disclosed. These novel forms were characterized by X-ray powder diffraction, differential scanning calorimetry, and other techniques. They can be readily prepared and are suitable for preparation of solid dosage forms owing to their ease of handling and superior pharmacological properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.