Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication

US10351546B2 · kind B2 · utility

Assignee

• ViiV Healthcare UK (No.5) Limited · GB

Inventors

• Kyle J. Eastman · New Haven, US
• John F. Kadow · Wallingford, US
• B. Narasimhulu Naidu · Durham, US
• Kyle E. Parcella · Wallingford, US
• Manoj Patel · Berlin, US
• Prasanna Sivaprakasam · Lawrenceville, US
• Yong Tu · Cheshire, US

Key dates

• Filing date: Aug 10, 2016
• Grant date: Jul 16, 2019
• Expiry date: Aug 10, 2036

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2300/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV.