Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain
US10351575B2 · kind B2 · utility
1Cited by
7References
48Claims
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Key dates
| Filing date | Nov 13, 2013 |
| Grant date | Jul 16, 2019 |
| Priority date | — |
| Expiry date | Oct 24, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of Formula I: or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.