Recombinant IgG4 monovalent antibodies
US10351629B2 · kind B2 · utility
1Cited by
6References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 17, 2016 |
| Grant date | Jul 16, 2019 |
| Priority date | — |
| Expiry date | Mar 17, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16011
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to novel non-human transgenic animals, which upon antigenic stimulation are capable of producing monovalent antibodies binding to a selected antigen, modified heavy chain transgenes, methods for producing the non-human transgenic animals, methods for immunizing the non-human transgenic animals for as well as monovalent antibodies obtainable by such immunization methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.