Glycoform detection method and glycoform detection device
US10352927B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 9, 2013 |
| Grant date | Jul 16, 2019 |
| Priority date | — |
| Expiry date | Aug 27, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2496/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
It is intended to develop and provide a method for detecting a particular glycan-isoform rapidly and specifically by a small number of steps. The present invention provides a glycan-isoform detection method comprising quantifying an immune complex formed by the mixing of a test sample with a sugar chain non-reducing terminal residue-binding lectin and an antibody specifically binding to the protein moiety of the glycan-isoform, etc., comparing the obtained amount of the immune complex with the amount of a control immune complex obtained when a control sample is not mixed with the sugar chain non-reducing terminal residue-binding lectin or is mixed with a control protein, and determining the presence or absence of the glycan-isoform of interest in the test sample on the basis of the difference between these amounts.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.