Patent · US Active

Optogenetic probes for measuring membrane potential

US10352945B2 · kind B2 · utility

4Cited by

31References

21Claims

0Family size

Assignee

President and Fellows of Harvard College · US

Inventors

Adam Cohen · Cambridge, US
Joel Kralj · Somerville, US
Adam D. Douglass · Salt Lake City, US

Key dates

Filing date	Oct 13, 2017
Grant date	Jul 16, 2019
Priority date	—
Expiry date	Oct 13, 2037

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/726
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention provides methods, cells and constructs for optical measurement of membrane potential. These methods can be used in cells that are not accessible to presently available methods using electrodes. The methods can be directed to, for example, high-throughput drug screening assays to determine agents that can affect membrane potential of a target cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.