Multiparticulates of spray-coated drug and polymer on a meltable core
US10357462B2 · kind B2 · utility
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34References
11Claims
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Key dates
| Filing date | Nov 19, 2007 |
| Grant date | Jul 23, 2019 |
| Priority date | — |
| Expiry date | Feb 1, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition comprises multiparticulates comprising a melt-congeal core and a solid amorphous dispersion layer of a poorly water soluble drug and polymer. The multiparticulates are suitable for improving bioavailability of poorly water soluble drugs. The melt-congeal cores facilitate application of the solid amorphous dispersion layer, and allow incorporation of additional optional components to the core so as to adjust the release of drug from the multiparticulate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.