Patent · US Active

Antiproliferative compounds and methods of use thereof

US10357489B2 · kind B2 · utility

12Cited by
11References
26Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 9, 2018
Grant dateJul 23, 2019
Priority date
Expiry dateJul 9, 2038

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2300/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein is 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof, and methods for treating, preventing or managing multiple myeloma using such compounds. Also provided are pharmaceutical compositions comprising the compounds, and methods of use of the compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.